This concept is based on strong scientific evidence from four key studies (HPTN-052 study, PARTNER study, Opposites Attract, PARTNER 2 study) involving couples where one partner was living with HIV and the other was not. These studies did not detect a single case of sexual transmission of HIV from a virally suppressed person living with HIV to their HIV-negative partner.
With U=U, HIV treatment has transformed the HIV prevention landscape. Not only does HIV treatment have life-changing individual benefits by enabling people living with HIV to stay healthy, maintain their quality of life and have a lifespan similar to people not living with HIV, it is now recognized to have important population health benefits by interrupting transmission of HIV. U=U can also have enormous benefits in reducing stigma and motivating people living with HIV to test, start and maintain treatment, become virally suppressed and continue follow-up care.”